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. Author manuscript; available in PMC: 2021 Mar 13.
Published in final edited form as: ACS Infect Dis. 2020 Jan 13;6(3):467–478. doi: 10.1021/acsinfecdis.9b00406

Figure 3. SAR summary of the TAT series.

Figure 3.

(A) 1,2,4-triazole and EcP10, representing the last ten amino acids at the C-terminal tail of E. coli SAT, are previously described CysK-targeted molecules. (B) Original TAT hit 1 and analogs. Color coding highlights regions of interest relative to the original hit 1. The E. coli MG1655 K12 MIC is shown for all compounds. Complete MIC data is listed in the Supplementary Table 2.