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Prostaglandin pathway and metabolism. Inhibitors of various steps are shown in red., COX-1, cyclooxygenase-1; EP4, Prostaglandin receptor 4; Indo, Indomethacin; Ibu, Ibuprofen; PG, prostaglandin; 15-PGDH, 15-hydroxyprostaglandin dehydrogenase; 15-KETO-PG2 (Figure courtesy of Fahri Ovali).
