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. Author manuscript; available in PMC: 2020 Sep 8.
Published in final edited form as: Hepatology. 2009 Apr;49(4):1335–1374. doi: 10.1002/hep.22759

Table 12.

Characteristics of Persons for Whom Therapy Is Currently Contraindicated

  • Major uncontrolled depressive illness

  • Solid organ transplant (renal, heart, or lung)

  • Autoimmune hepatitis or other autoimmune condition known to be exacerbated by peginterferon and ribavirin

  • Untreated thyroid disease

  • Pregnant or unwilling to comply with adequate contraception

  • Severe concurrent medical disease such as severe hypertension, heart failure, signioficant coronary heart disease, poorly controlled diabetes, chronic obstructive pulmonary disease

  • Age less than 2 years

  • Known hypersensitivity to drugs used to treat HCV