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. 2020 Aug 25;11:2080. doi: 10.3389/fmicb.2020.02080

TABLE 3.

Comparison of FAPP and culture for each FAPP bacterial target, at the time of HAP diagnosis.

FAPP Bacterial targets BALDS (number of results for FAPP/culture) ETADS(number of results for FAPP/culture)


(+ / +) (+ /−) (−/ +) (−/−) PPA (95% CI) NPA (95% CI) OPA (95% CI) (+ / +) (+ /−) (−/ +) (−/−) PPA (95% CI) NPA (95% CI) OPA (95% CI)
A. baumannii 0 0 0 76 NA 100 [100; 100] 100 [100; 100] 0 0 0 82 NA 100 [100; 100] 100 [100; 100]
E. cloacae 2 3 0 71 100 [100; 100] 96 [92; 100] 96 [92; 100] 2 3 0 77 100 [100; 100] 96 [92; 100] 96 [92; 100]
E. coli 15 2 0 59 100 [100; 100] 97 [94; 100] 97 [94; 100] 9 0 0 73 100 [100; 100] 100 [100; 100] 100 [100; 100]
H. influenzae 23 9 0 44 100 [100; 100] 83 [73; 93] 88 [81; 95] 20 14 1 47 95 [86; 100] 77 [66; 88] 82 [73; 90]
K. aerogenes 0 0 0 76 NA 100 [100; 100] 100 [100; 100] 0 0 0 82 NA 100 [100; 100] 100 [100; 100]
K. oxytoca 2 4 1 69 67 [13; 100] 95 [89;100] 93 [88; 99] 2 4 0 76 100 [100; 100] 95 [90; 100] 95 [90; 100]
K. pneumoniae 7 2 0 67 100 [100; 100] 97 [94; 100] 97 [94; 100] 6 1 0 75 100 [100; 100] 99 [96; 100] 99 [96; 100]
M. catarrhalis 0 2 0 74 NA 97 [94; 100] 97 [94; 100] 1 4 0 77 100 [100; 100] 95 [90; 100] 95 [90; 100]
Proteus spp. 1 4 0 71 100 [100; 100] 95 [90; 100] 95 [90; 100] 4 4 0 74 100 [100; 100] 95 [90; 100] 95 [90; 100]
P. aeruginosa 3 0 0 73 100 [100; 100] 100 [100; 100] 100 [100; 100] 3 0 0 79 100 [100; 100] 100 [100; 100] 100 [100; 100]
S. marcescens 1 1 0 74 100 [100; 100] 99 [96; 100] 99 [96; 100] 0 3 0 79 NA 96 [92; 100] 96 [92; 100]
S. aureus 17 6 0 53 100 [100; 100] 90 [82; 98] 92 [86; 98] 19 5 0 58 100 [100; 100] 92 [85; 99] 94 [89; 99]
S. agalactiae 1 3 0 72 100 [100; 100] 96 [92; 100] 96 [92; 100] 0 4 0 78 NA 95 [90; 100] 95 [90; 100]
S. pneumoniae 11 4 0 61 100 [100; 100] 94 [88; 100] 95 [90; 100] 9 4 0 69 100 [100; 100] 95 [90; 100] 95 [90; 100]
S. pyogenes 0 1 0 75 NA 99 [96; 100] 99 [96; 100] 0 0 0 82 NA 100 [100; 100] 100 [100; 100]
Total 83 41 1 1015 99 [96; 100] 96 [95; 97] 96 [95; 97] 75 46 1 1108 99 [96; 100] 96 [95; 97] 96 [95; 97]