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. 2020 Sep 2;7(5):ENEURO.0012-19.2020. doi: 10.1523/ENEURO.0012-19.2020

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Copyright © 2020 Torero Ibad et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 7. — Inner retinal function. A, Extracted oscillatory potential traces of a PV^Cre mouse (left) and PV^Cre::scFvOTX2^tg/o mouse (right). B, The amplitude of an early OP (OP2) is not altered in the PV^Cre::scFvOTX2^tg/o mice, while the amplitude of a late OP (OP4) is significantly reduced by ∼50%. C, Representative traces of 20 Hz flickers of the left eye of mice of the two genotypes. D, The amplitude of the flicker response to 10 Hz stimulation after light adaptation is slightly increased, and at 20 Hz the response is significantly doubled in amplitude. Bottom, There was no difference in the implicit time of the flicker responses between mice expressing OTX2scFv and their PV^Cre littermates. ***p < 0.005, Mann–Whitney U test, two tailed. N = 7 for PV^Cre and N = 9 for PV^Cre::scFvOTX2^tg/o mice. Values mean ± sem.