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. 2019 Aug 21;10(11):1881–1891. doi: 10.1039/c9md00305c

Table 1. IC50 values of TOTA, Pr-ADOTA and Pr-DAOTA against breast (MDA-MB-231) and colon (HCT116) cancer cell lines (SD – standard deviation).

Compound MDA-MB-231 SD HCT116 SD
IC50 (nM) IC50 (nM)
Camptothecin 28.4 0.8 8.5 0.9
TOTA 448.5 46.5 707.5 64.5
Pr-ADOTA 87.5 37.6 256.5 3.5
Pr-DAOTA 77.5 27.0 106.5 5.5