Table 3.
Characteristics after return of spontaneous circulation and outcome of patients receiving TTM
| IHCA (N = 93) | OHCA (N = 93) | p | |
|---|---|---|---|
| SOFA within 24 hours after event | |||
| Mean (SD) | 9.5 (2.4) | 8.4 (2.7) | 0.004* |
| Median (IQR) | 9 (8-11) | 8 (7-11) | |
| Glucose (mg/dL), mean (SD) | 199.1 (101.9) | 259.6 (193.1) | 0.002* |
| MAP (mmHg), mean (SD) | 73.1 (16.1) | 85.5 (24.0) | <0.001* |
| pH, mean (SD) | 7.28 (0.17) | 7.27 (0.16) | 0.896 |
| Lactate (mmol/L), mean (SD) | 5.6 (5.3) | 5.8 (3.9) | 0.226 |
| Creatinine (mg/dL), mean (SD) | 2.3 (2.2) | 1.8 (1.3) | 0.413 |
| Coagulopathy after TTM, N (%) | |||
| Thrombocytopenia <150 K/μL | 48 (51.6) | 29 (31.2) | 0.004* |
| Thrombocytopenia <50 K/μL | 7 (7.5) | 1 (1.1) | 0.064 |
| Thrombocytopenia <20 K/μL | 0 (0.0) | 0 (0.0) | … |
| Prolonged PT >14.4 s | 62 (66.7) | 57 (61.3) | 0.276 |
| Prolonged aPTT >36,6 s | 36 (38.7) | 31 (33.3) | 0.549 |
| Electrolyte imbalance after TTM, N (%) | |||
| Hypernatremia, sodium >145mmol/L | 7 (7.5) | 2 (2.2) | 0.090 |
| Hyponatremia, sodium <136 mmol/L | 26 (28.0) | 24 (25.8) | 0.774 |
| Hyperkalemia, potassium >5.0 mmol/L | 9 (9.7) | 13 (14.0) | 0.344 |
| Hypokalemia, potassium <3.4 mmol/L | 4 (4.3) | 6 (6.5) | 0.502 |
| Outcome | |||
| Subsequent LOS, mean (SD) | 19.7 (28.4) | 12.7 (11.7) | 0.025* |
| Acute kidney injury, N (%) | 28 (30.1) | 27 (29.0) | 0.830 |
| Survival to discharge, N (%) | 50 (53.8) | 42 (45.2) | 0.241 |
| Favorable CPC scale at discharge, N (%) | 24 (25.8) | 26 (28.0) | 0.182 |
TTM = targeted temperature management; IHCA = in-hospital cardiac arrest; OHCA = out-of-hospital cardiac arrest; SOFA = sequential organ failure assessment; IQR= interquartile range; MAP = mean arterial pressure; PT = prothrombin time; aPTT = activated partial thromboplastin time; LOS = length of hospital stay; CPC scale = cerebral performance category scale.
*p < 0.05.