Table 4.
Logistic regression analysis of predictors of survival at discharge among patients receiving TTM in this cohort
| Univariable analysis | Multivariable analysis | |||
|---|---|---|---|---|
| Odds ratio (95% CI) | p | Odds ratio (95% CI) | p | |
| IHCA | 1.412 (0.793–2.514) | 0.241 | ||
| Age | 0.998 (0.978–1.020) | 0.877 | ||
| Sex, male | 1.419 (0.772–2.607) | 0.260 | ||
| Charlson score | 1.075 (0.966–1.196) | 0.185 | ||
| Initial shockable rhythm | 3.173 (1.657–6.078) | <0.001 | 3.876 (1.876–8.008) | <0.001* |
| Time to ROSC | 0.966 (0.943–0.989) | 0.004 | 0.966 (0.940–0.992) | 0.011* |
| Witnessed cardiac arrest | 1.687 (0.874–3.260) | 0.119 | ||
| Bystander CPR | 1.348 (0.736–2.470) | 0.333 | ||
| Total dosage of epinephrine | 0.855 (0.764–0.957) | 0.006 | ||
| Presumed cardiac cause | 1.857 (1.000–3.448) | 0.050 | ||
| Coronary artery disease | 2.195 (1.219–3.953) | 0.009 | ||
| Arrhythmia | 1.134 (0.632–2.035) | 0.674 | ||
| Heart failure | 2.202 (1.168–4.149) | 0.015 | 2.589 (1.269–5.283) | 0.009* |
| Cerebrovascular disease | 1.203 (0.550–2.632) | 0.644 | ||
| Thrombocytopenia (PLT < 150,000) | 1.073 (0.584–1.972) | 0.821 | ||
| Hypokalemia | 0.413 (0.103–1.653) | 0.211 | ||
| Glucose level after ROSC | 0.998 (0.995–1.000) | 0.114 | ||
| SOFA within 24 hours after event | 0.901 (0.801–1.014) | 0.083 | ||
| Mean arterial pressure | 1.003 (0.989–1.017) | 0.665 | ||
TTM = targeted temperature management; IHCA = in-hospital cardiac arrest; ROSC = return of spontaneous circulation; CPR = cardiopulmonary resuscitation; PLT = platelet; SOFA = sequential organ failure assessment.
*p < 0.05.