Table 5.
Logistic regression analysis of predictors of favorable neurological outcome among survivors after TTM
| Univariable analysis | Multivariable analysis | |||
|---|---|---|---|---|
| Odds ratio (95% CI) | p | Odds ratio (95% CI) | p | |
| IHCA | 0.568 (0.247–1.308) | 0.184 | ||
| Age | 1.015 (0.983–1.049) | 0.364 | ||
| Sex, male | 1.581 (0.647–3.863) | 0.315 | ||
| Charlson score | 1.027 (0.879–1.201) | 0.734 | ||
| Initial shockable rhythm | 5.221 (2.099–12.986) | <0.001 | 6.570 (2.435–17.728) | <0.001* |
| Time to ROSC | 0971 (0.933–1.010) | 0.145 | ||
| Witnessed cardiac arrest | 1.616 (0.597–4.380) | 0.345 | ||
| Bystander CPR | 0.631 (0.257–1.549) | 0.315 | ||
| Total dosage of epinephrine | 0.749 (0.600–0.934) | 0.010 | ||
| Presumed cardiac cause | 3.757 (1.524–9.257) | 0.004 | ||
| Coronary artery disease | 1.795 (0.781–4.126) | 0.168 | ||
| Arrhythmia | 1.155 (0.503–2.654) | 0.733 | ||
| Heart failure | 0.681 (0.294–1.575) | 0.369 | ||
| Cerebrovascular disease | 0.810 (0.275–2.382) | 0.701 | ||
| Thrombocytopenia (PLT < 150,000) | 1.182 (0.497–2.810) | 0.706 | ||
| Hypokalemia | 0.409 (0.036–4.696) | 0.473 | ||
| Glucose level after ROSC | 0.999 (0.995–1.003) | 0.709 | ||
| SOFA within 24 hours after event | 0.821 (0.686–0.982) | 0.031 | ||
| Mean arterial pressure | 1.017 (0.995–1.039) | 0.130 | ||
TTM = targeted temperature management; IHCA = in-hospital cardiac arrest; ROSC = return of spontaneous circulation; CPR = cardiopulmonary resuscitation; PLT = platelet; SOFA = sequential organ failure assessment.
*p < 0.05.