Table 2.
Variable | OW (N = 15) | DM (N = 9) | DM/OW (N = 16) |
---|---|---|---|
Anthropometric# | |||
Gender M/F (%M) | 5/10 (33.3%) | 9/0 (100%) | 5/11 (68.7%) |
Male age (year/range) | 37.0a (32–42) | 54.4b (42–63) | 54.2b (41–72) |
Female age (year/range) | 34.4a (23–45) | — | 45.9b (32–65) |
Height (cm) | 162a ± 1.71 | 173b ± 2.82 | 158a ± 2.62 |
Weight (kg) | 74.1a ± 1.98 | 69.4a ± 1.88 | 74.5a ± 3.22 |
BMI (kg/m2) | 28.3b ± 0.657 | 23.3a ± 0.439 | 29.6b ± 0.776 |
Waist (cm) | 92.1a ± 1.92 | 90.4a ± 1.72 | 97.3b ± 2.36 |
Hip (cm) | 108b ± 1.60 | 97.9a ± 0.920 | 106b ± 2.55 |
Waist/hip | 0.857a ± 0.0206 | 0.924b ± 0.0147 | 0.917b ± 0.0191 |
Index of central obesity | 0.569a ± 0.00995 | 0.525a ± 0.0116 | 0.615b ± 0.0129 |
Glycemic# | |||
HbA1c ≥7.0 (% of subjects in group) | 0/15 (0.0%)a | 7/9 (77.8%)b | 12/16 (75%)b |
HbA1c (%) | 5.29a ± 0.0661 | 7.92b ± 0.398 | 7.97b ± 0.392 |
FBG (mg/dL) | 92.9a ± 1.99 | 137b ± 15.1 | 164b ± 11.3 |
PPBG (mg/dL) | 129a ± 4.30 | 228b ± 24.7 | 232b ± 14.9 |
eAG (mg/dL) | 105a ± 1.90 | 181b ± 11.4 | 182b ± 11.2 |
Vascular# | |||
SBP (mmHg) | 120a ± 2.05 | 123a ± 2.89 | 126a ± 2.88 |
DBP (mmHg) | 76.9a ± 1.36 | 80.7a ± 3.56 | 80.9a ± 2.26 |
MAP (mmHg) | 91.3a ± 1.28 | 94.9a ± 3.08 | 95.9a ± 2.35 |
PP (mmHg) | 43.2a ± 2.09 | 42.7a ± 2.77 | 45.0a ± 1.70 |
Lipidic# | |||
TC (mg/dL) | 214a ± 7.41 | 197a ± 8.83 | 196a ± 11.0 |
TC-HDL (mg/dL) | 174a ± 7.25 | 157a ± 9.03 | 157a ± 10.7 |
LDL (mg/dL) | 137a ± 7.13 | 127a ± 8.47 | 126a ± 9.45 |
VLDL (mg/dL) | 32.3a ± 1.88 | 30.9a ± 2.95 | 27.8a ± 2.12 |
HDL (mg/dL) | 39.9a ± 0.888 | 39.7a ± 0.289 | 38.5a ± 0.585 |
TG (mg/dL) | 163a ± 9.39 | 156a ± 14.7 | 139a ± 11.1 |
Lipidic ratios# | |||
TC/HDL | 5.38a ± 0.194 | 4.98a ± 0.249 | 5.07a ± 0.255 |
LDL/HDL | 3.43a ± 0.172 | 3.20a ± 0.227 | 3.25a ± 0.221 |
VLDL/HDL | 0.815a ± 0.0498 | 0.782a ± 0.0782 | 0.719a ± 0.0506 |
TG/HDL | 4.21a ± 0.297 | 3.69a ± 0.285 | 3.53a ± 0.323 |
Hepatic# | |||
GGT (IU/L) | 16.5a ± 1.07 | 23.1b ± 1.97 | 15.7a ± 1.93 |
AST (IU/L) | 28.8a ± 1.92 | 41.4b ± 5.83 | 30.0a ± 2.57 |
ALT (IU/L) | 35.7ab ± 2.64 | 44.3b ± 5.58 | 31.6a ± 2.47 |
AST/ALT | 0.836a ± 0.0564 | 0.925a ± 0.0450 | 0.976a ± 0.0695 |
ALP (IU/L) | 148a ± 8.45 | 175a ± 17.9 | 167a ± 13.5 |
Bilirubin (mg/dL) | 0.653a ± 0.0477 | 0.611a ± 0.0807 | 0.644a ± 0.0545 |
Direct bilirubin (mg/dL) | 0.220a ± 0.0200 | 0.222a ± 0.0465 | 0.213a ± 0.0256 |
Total protein (mg/dL) | 6.59a ± 0.108 | 6.88a ± 0.134 | 6.76a ± 0.102 |
Albumin (g/dL) | 4.27a ± 0.114 | 4.39a ± 0.170 | 4.36a ± 0.104 |
Globulin (g/dL) | 2.32a ± 0.104 | 2.43a ± 0.124 | 2.41a ± 0.0566 |
A/G | 1.93a ± 0.160 | 1.86a ± 0.163 | 1.83a ± 0.0676 |
Renal# | |||
BUN (mg/dL) | 24.5a ± 1.29 | 23.0a ± 1.74 | 26.8a ± 1.56 |
Creatinine (mg/dL) | 0.880a ± 0.0327 | 0.989a ± 0.0484 | 0.994a ± 0.0295 |
BUN/creatinine | 28.6a ± 2.22 | 23.2a ± 1.17 | 27.3a ± 1.91 |
Thyroid# | |||
T3 (ng/mL) | 1.16a ± 0.0475 | 1.17a ± 0.0512 | 1.17a ± 0.0616 |
T4 (mg/dL) | 7.83a ± 0.483 | 8.00a ± 0.299 | 7.90a ± 0.655 |
TSH (mg/dL) | 3.19a ± 0.439 | 2.77a ± 0.306 | 3.48a ± 0.584 |
Metabolic syndrome# | |||
Number of diagnostic criteria met | 2.20a ± 0.296 | 2.33a ± 0.167 | 3.31b ± 0.254 |
Cardiometabolic indices## | |||
Cardiovascular risk (%) | 1.20a (0.700–2.90) | 11.9b (4.20–23.1) | 3.75b (0.800–38.8) |
Fatty liver index (score) | 42.0b (25.0–80.0) | 34.0a (24.0–45.0) | 50.0b (25.0–84.0) |
Lipid accumulation product (score) | 58.1b (27.8–115) | 41.2a (29.2–57.6) | 52.4ab (31.7–98.2) |
Hepatic steatosis index (score) | 39.1b (34.6–48.8) | 33.5a (32.2–36.8) | 38.4b (31.9–46.3) |
Values are mean ± SEM; common letter superscripts indicate nonsignificant differences P > .05 determined by ANOVA.
Values are medians with parenthetic range; common letter superscripts indicate nonsignificant differences P > .05 determined by Kruskal–Wallis test.
ALP, alkaline phosphatase; ALT, alanine transaminase; AST, aspartate aminotransferase; BMI, body mass index; BUN, blood urea nitrogen; DBP, diastolic blood pressure; DM, diabetic; OW, overweight; eAG, estimated average glucose; FBG, fasting blood glucose; GGT, gamma-glutamyl transferase; HbA1c, glycated hemoglobin; HDL, high density lipoprotein; ICO, index of central obesity; LDL, low density lipoprotein; MAP, mean arterial pressure; OW, over weight; PP, pulse pressure; PPG, postprandial glucose; SBP, systolic blood pressure; T3, triiodothyronine; T4, thyroxine; TC, total cholesterol; TG, triglycerides; TSH, thyroid stimulating hormone; VLDL, very low density lipoprotein; SEM, standard error of mean; ANOVA, analysis of variance.