Kaplan-Meier analysis of subjects in a pooled COPDGene and ECLIPSE sample. A, Subjects were grouped by BODE score (0-2, 3-4, 5-6, 7-10). B, Subjects were stratified into four groups based on the machine learning mortality prediction (MLMP)-COPD model. Participants were ranked according to their calculated risk by the MLMP-COPD model and divided into four groups of mortality risk that were of equal size as those of the BODE groups. Circles indicate the probability of survival at each time point, and the bars are 95% CIs. See Figure 1 and 3 legends for expansion of other abbreviations.