Table 3.
Characteristics of Subjects With the Highest Predicted Mortality
| Characteristic | BODE Group | Model Group | P Value |
|---|---|---|---|
| No. of subjects | 184 | 184 | … |
| Age, mean (SD), y | 63.76 (7.47) | 69.83 (6.44) | < .001 |
| Race, African American, No. (%) | 18 (9.8) | 16 (8.7) | .857 |
| Sex, female, No. (%) | 82 (44.6) | 57 (31.0) | .010 |
| Total dead, No. (%) | 118 (64.1) | 141 (76.6) | .012 |
| Days followed up, median (IQR) | 1,280.50 (940.50-2,243.50) | 1,192.50 (791.75-1,833.75) | .049 |
| BODE, median (IQR) | 7.00 (7.00-8.00) | 6.00 (5.00-7.00) | < .001 |
| 6-Min walk distance, mean (SD), ft | 608.18 (343.20) | 593.19 (263.68) | .639 |
| FEV1 % predicted, median (IQR) | 27.65 (21.60-33.28) | 28.10 (20.88-34.38) | .942 |
| mMRC dyspnea score, No. (%) | .009 | ||
| 1 | 0 (0.0) | 5 (2.7) | |
| 2 | 19 (10.3) | 32 (17.4) | |
| 3 | 58 (31.5) | 64 (34.8) | |
| 4 | 107 (58.2) | 83 (45.1) | |
| FEV1/FVC ratio, median (IQR) | 0.34 (0.28-0.41) | 0.33 (0.27-0.37) | .053 |
| FEF25%-75%, median (IQR), L | 0.24 (0.19-0.33) | 0.23 (0.17-0.30) | .080 |
| Resting SaO2, median (IQR) | 94.00 (91.00-96.00) | 93.00 (88.00-94.25) | < .001 |
| Exacerbation frequency, mean (SD), No./y | 1.26 (1.33) | 1.52 (1.57) | .086 |
| Pack-years cigarette smoking, median (IQR) | 45.00 (34.60-67.62) | 61.40 (40.00-88.92) | < .001 |
| BMI, mean (SD), kg/m2 | 23.81 (6.30) | 25.47 (5.63) | .008 |
| Severe exacerbations, No. (%) | 86 (46.7) | 95 (51.6) | .404 |
| PA:A ratio, mean (SD) | 0.97 (0.16) | 1.02 (0.18) | .006 |
| Pi10, mean (SD) | 4.12 (0.35) | 4.10 (0.37) | .611 |
| Diabetes, No. (%) | 20 (10.9) | 38 (20.7) | .015 |
| % LAA < −950 HU, median (IQR) | 30.80 (18.50-39.40) | 24.48 (15.83-36.96) | .021 |