Table 2.
Multivariable Analysis of Association of SP-D With PARDS or Severe PARDS in Children With Acute Respiratory Failure
| Variable | OR | 95% CI | P |
|---|---|---|---|
| PARDS | |||
| SP-D | 1.02 | 1.00, 1.03 | .059 |
| Age | 1.00 | 0.96, 1.05 | .913 |
| PRISM III | 1.04 | 1.01, 1.08 | .020 |
| Primary diagnosis | .095 | ||
| Pneumonia | Ref | ||
| Bronchiolitis | 1.10 | 0.53, 2.30 | .791 |
| Sepsis | 0.80 | 0.41, 1.56 | .511 |
| Asthma | 0.48 | 0.23, 1.00 | .051 |
| Aspiration Pneumonia | 0.54 | 0.21, 1.34 | .182 |
| Other | 0.35 | 0.14, 0.89 | .027 |
| Severe PARDS | |||
| SP-D | 1.02 | 1.01, 1.04 | .011 |
| Age | 1.04 | 1.00, 1.09 | .052 |
| PRISM III | 1.05 | 1.02, 1.08 | .004 |
| Primary diagnosis | .028 | ||
| Pneumonia | Ref | ||
| Bronchiolitis | 0.55 | 0.25, 1.22 | .140 |
| Sepsis | 0.56 | 0.30, 1.07 | .080 |
| Asthma | 0.26 | 0.10, 0.66 | .004 |
| Aspiration Pneumonia | 0.70 | 0.28, 1.76 | .446 |
| Other | 0.32 | 0.12, 0.88 | .027 |
N = 350 total; n = 233 with PARDS, n = 120 severe PARDS. ref = reference; SP-D = surfactant protein-D.
See Table 1 legend for expansion of other abbreviations.