Figure 2.
Kidney cross-sections to show Bowman space, vascular congestion, and cellular necrosis in different experimental groups. a) rats with no intervention (control); b) rats undergone surgery without renal vessel clamping and receiving PBS solution and equivalent 48-hr reperfusion period (Sham); c) rats with 45 min of ischemia and 48 hr of reperfusion receiving PBS (I/R 48 hr + PBS), yellow arrows show vascular congestion; and d) rats with 45 min of ischemia and 48 hr of reperfusion pretreated with 2 × 106 AD-MSC (I/R 48 hr + stem cell), yellow arrows show damaged thick ascending limbs of Henle’s loops. 400x magnification; Hematoxylin-Eosin staining
IR: ischemia-reperfusion; AD-MSC: adipose-derived mesenchymal stem cells