Table 2.
Effect of ginkgolide B on left ventricular hemodynamic parameters in diabetic rats
| Normal control | Diabetes model | Ginkgolide B treatment | |
|---|---|---|---|
| SP (mmHg) | 136.1 ± 6.45 | 102.4 ± 7.60** | 117.5 ± 9.52$$ |
| DP (mmHg) | 98.6 ± 6.14 | 67.4 ± 6.09** | 83.4 ± 8.14$$ |
| +dP/dtmax (mmHg/s) |
4383.1 ± 111.9 | 3062.3 ± 130.7** | 3615.8 ± 127.1$$ |
| -dP/dtmax (mmHg/s) |
4377.4 ± 75.1 | 3079.4 ± 117.7** | 3629.6 ± 129.4$$ |
| Heart rates (/s) |
353 ± 8.65 | 301 ± 16.58** | 332 ± 18.15$$ |
Values are expressed as mean±SEM. Data were analyzed by unpaired t-test or by one-way ANOVA, followed by Tukey test correction for multiple comparisons. **Represents P<0.01, comparison between normal control and diabetes model group, $$ Represents P<0.01, comparison between diabetes model and ginkgolide B treatment group. SP: Systolic pressure; DP: Diastolic pressure; +dP/dtmax: maximum rate of rise of left ventricle pressure; -dP/dtmax: maximum rate of fall of left ventricle pressure