Table 4. Histological evaluation of angiogenesis after 4 weeks of open fracture with Staphylococcus aureus contamination in rats according to each group.
| Groups (n =52) | Angiogenesis | |||
|---|---|---|---|---|
| Mild | Intense | |||
| N | % | N | % | |
| A (n= 11) | 9 | 81.8 | 2 | 18.2 |
| B (n= 8) | 4 | 50.0 | 4 | 50.0 |
| C (n= 8) | 5 | 62.5 | 3 | 37.5 |
| D (n= 7) | 5 | 71.4 | 2 | 28.6 |
| E (n= 8) | 5 | 62.5 | 3 | 37.5 |
| F (n= 10) | 6 | 60.0 | 4 | 40.0 |
p = 0.802; Groups: A – no treatment; B – Systemic ciprofloxacin; C – Chitosan impregnated rod; D – Chitosan impregnated rod with 10% ciprofloxacin; E – Chitosan impregnated rod with 25% ciprofloxacin; F – Chitosan impregnated rod with 50% ciprofloxacin.