Table 5. Histological evaluation of fibroplasia (conjunctive dense tissue) after 4 weeks of open fracture with Staphylococcus aureus contamination in rats according to each group.
| Groups (n =52) | Fibroplasia | |||
|---|---|---|---|---|
| Mild | Intense | |||
| N | % | n | % | |
| A (n =11) | 5 | 45.5 | 6 | 54.5 |
| B (n =8) | 7 | 87.5 | 1 | 12.5 |
| C (n =8) | 6 | 75.0 | 2 | 25.0 |
| D (n =7) | 3 | 42.9 | 4 | 57.1 |
| E (n =8) | 5 | 65.2 | 3 | 37.5 |
| F (n =10) | 5 | 50.0 | 5 | 50.0 |
p >0.05; Groups: A – no treatment; B – Systemic ciprofloxacin; C – Chitosan impregnated rod; D – Chitosan impregnated rod with 10% ciprofloxacin; E – Chitosan impregnated rod with 25% ciprofloxacin; F – Chitosan impregnated rod with 50% ciprofloxacin.