Table 3. Cox proportional hazards regression analysis of time to HIV testing among sexual contacts of HIV-positive index clients in Siaya County, Kenya.
Time to Testing | Univariable | Multivariable (Main Model) | Multivariable (Time-Varying Covariate)* | |||
---|---|---|---|---|---|---|
HR (95% CI) | P value | aHR (95% CI) | P value | aHR (95% CI) | P value | |
Age, years§ | ||||||
18–24 | 1.32 (1.15–1.51) | <0.001 | 1.32 (1.01–1.73) | 0.04 | 0.94 (0.87–1.02) | 0.153 |
25–34 | 1.14 (1.04–1.24) | 0.005 | 1.18 (1.01–1.39) | 0.038 | 0.96 (0.9–1.01) | 0.126 |
35–44 | Ref | Ref | Ref | |||
≥45 | 1.03 (0.89–1.18) | 0.727 | 0.96 (0.79–1.18) | 0.727 | 1.02 (0.95–1.11) | 0.54 |
Sex | ||||||
Female | 1.10 (1–1.2) | 0.04 | 0.95 (0.81–1.1) | 0.496 | - | - |
Male | Ref | Ref | ||||
Marital Status§^ | ||||||
Married Monogamous | Ref | Ref | Ref | |||
Married Polygamous | 0.93 (0.73–1.17) | 0.527 | 0.78 (0.54–1.12) | 0.174 | 1.12 (1.01–1.25) | 0.039 |
Single | 1.58 (1.25–2) | <0.001 | 0.71 (0.51–1) | 0.05 | 1.17 (1.08–1.27) | <0.001 |
Unknown | 1.18 (0.98–1.41) | 0.079 | 0.43 (0.3–0.64) | <0.001 | 1.25 (1.14–1.38) | <0.001 |
Widowed | 1.18 (0.77–1.81) | 0.456 | 0.71 (0.29–1.74) | 0.459 | 1.08 (0.82–1.42) | 0.588 |
Relationship to Index Client§^ | ||||||
Non-spouse Sexual Contact | 1.68 (1.44–1.96) | <0.001 | 1.12 (0.84–1.48) | 0.444 | 1.23 (1.15–1.32) | <0.001 |
Spouse | Ref | Ref | Ref | |||
Sub-County§ | ||||||
Alego Usonga | 1.49 (1.07–2.08) | 0.019 | 1.90 (1.14–3.17) | 0.014 | 0.90 (0.77–1.05) | 0.186 |
Bondo | 1.42 (1.02–1.97) | 0.037 | 1.47 (0.92–2.35) | 0.11 | 0.95 (0.82–1.09) | 0.449 |
Gem | 1.28 (0.98–1.67) | 0.067 | 1.06 (0.73–1.54) | 0.755 | 1.09 (0.93–1.28) | 0.27 |
Rarieda | 1.65 (1.24–2.18) | 0.001 | 1.39 (0.9–2.15) | 0.14 | 1.07 (0.91–1.25) | 0.425 |
Ugenya | Ref | Ref | Ref | |||
Ugunja | 1.15 (0.82–1.61) | 0.417 | 0.71 (0.4–1.26) | 0.242 | 1.20 (1.01–1.42) | 0.038 |
*Time-varying covariate interacted with natural logarithm of time
§Violated proportional hazards assumptions and was included as a time-varying covariate in Cox model
^Significant time-varying covariate interaction
Abbreviations: HR, hazards ratio; CI, confidence interval; aHR, adjusted hazards ratio.