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. 2020 Aug 5;12(8):e9578. doi: 10.7759/cureus.9578

Table 2. Articles published demonstrating association of coffee/caffeine consumption with cognitive impairment.

CI, confidence interval; RR, relative risk; OR, odds ratio; HR, hazard ratio.

Authors (reference) Year of publication range Type of study Number of participants Parameter used with 95% CI Association found (yes/no)
Dong X et al. [30] 2011-2014 Meta-analysis 2,513 OR: 0.56 (0.35-0.89) Yes
Wu L et al. [31] Inception-2016 Meta-analysis 34,282 RR: 0.82 (0.71-0.94) Yes
Santos C et al. [32] 1989-2009 Systematic review/meta-analysis - RR: 0.84 (0.72-0.99) Yes
KIm YS et al. [33] Inception-2014 Meta-analysis 31,479 OR/RR: 0.83 (0.70-0.98)  No
Solfrizzi V et al. [39] - Longitudinal study 1,445 HR: 0.26 (0.03-2.11) no