Fig. 1.

Phylogenetic trees of the family Lachnospiraceae . (a) Full-length 16S rRNA gene maximum-likelihood tree from 1000 bootstrap replicates is shown. Genera other than Roseburia were collapsed to simplify visualization of the tree. The fully expanded tree including accession numbers can be found in Fig. S1. (b) The 18-gene concatenated maximum-likelihood tree from 100 bootstrap replicates is shown with collapsed nodes and the fully expanded tree can be found in Fig. S2. (Bootstrap scores >70 are reported). (c) Roseburia core genome(s) displaying the overlapping orthologous protein encoding genes among the species evaluated. (d) Pairwise comparison of orthologies among Roseburia sp. Rows are coloured according to the species and numbers along the diagonal represent the core genome for a given species.