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. 2020 Jun 5;217(9):e20192152. doi: 10.1084/jem.20192152

Figure S2.

Figure S2.

Transfer of JEV-immune IgG exacerbates lethal ZIKV infection in mice. (A–D) 1-d-old naive C57BL/6 mice were injected s.c. with (A and B) 75 µg of IgG purified from JEV-naive (n = 12) or JEV-immune (n = 8) human sera or (C and D) 12 µg of IgG purified from mock-immune (n = 15) or JEV-immune (n = 13) mice and injected s.c. with ZIKV (102 FFU) 6 h later. Weights and survival were recorded daily for up to 28 d. Data are presented as the mean ± SD and are pooled from two experiments, each with four to eight mice/group. *, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, P < 0.0001 by two-tailed Mann–Whitney U test (A and C) or log-rank test (B and D).