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SPIRIT figure: Schedule of enrollments, interventions, and assessments. [1] Lung function tests: FEV1, forced expiratory volume in one second; FVC, forced volume capacity. [2] Laboratory tests: blood, urine, feces, electrocardiogram, and kidney and liver function tests. 6MWT = 6-minute walk test, CAT = COPD assessment test, SGRQ = St George's Respiratory Questionnaire.
