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. 2020 Jul 23;152(9):e202012606. doi: 10.1085/jgp.202012606

Table 1. Distributions of open durations for wild-type α7 nAChR.

[ACh] Calcium free 1.8 mM Ca2+
Mean open, s Weight Mean open, s Weight
1 µM 1.2 × 10−5 ± 1.7 × 10−6 1.0 1.5 × 10−5 ± 3.7 × 10−6 1.0 × 10−4 ± 9.7 × 10−6 0.67 ± 0.02 0.33 ± 0.02
n = 3 n = 6
10 µM 1.0 × 10−5 ± 1.2 × 10−6 6.1 × 10−5 ± 6.4 × 10−6 0.90 ± 0.03 0.10 ± 0.06 1.1 × 10−5 ± 1.3 × 10−6 1.2 × 10−4 ± 3.4 × 10−5 0.58 ± 0.06 0.41 ± 0.06
n = 6 n = 4 n = 4
100 µM 1.2 × 10−5 ± 1.6 × 10−6 8.9 × 10−5 ± 1.6 × 10−6 0.55 ± 0.03 0.45 ± 0.3 1.2 × 10−5 ± 1.7 × 10−6 9.5 × 10−5 ± 8.5 × 10−6 0.59 ± 0.04 0.41 ± 0.04
n = 6 n = 6

Time constants and relative weights of exponential components were obtained by fitting open-duration histograms for n experiments.