OSM alone | 4:1 mixture | 2:1 mixture | 1:1 mixture | 1:2 mixture |
1:4 mixture | BAY alone | |
---|---|---|---|---|---|---|---|
osimertinib EC50 (nM) |
2.62 | 0.84 | 0.70 | 0.92 | 1.49 | 1.19 | 2.40 |
BAY-293 EC50 (μM) |
2.14 | 1.01 | 0.83 | 1.09 | 1.49 | 1.04 | 1.82 |
OSM alone | 4:1 mixture | 2:1 mixture | 1:1 mixture | 1:2 mixture |
1:4 mixture | BAY alone | |
---|---|---|---|---|---|---|---|
osimertinib EC50 (nM) |
2.62 | 0.84 | 0.70 | 0.92 | 1.49 | 1.19 | 2.40 |
BAY-293 EC50 (μM) |
2.14 | 1.01 | 0.83 | 1.09 | 1.49 | 1.04 | 1.82 |