FIGURE 6.

JUN involves in PTX3 mediated cell autophagy. (A) Cells proliferation was inhibited by silenced PTX3 expression. JUN overexpression promoted tumor cells proliferation, but it can be reversed by silenced PTX3 expression. (B) Western bolt suggested that JUN overexpression inhibited the LC3B-I to LC3B-II transition along with increased PTX3 expression. By simultaneously silenced PTX3 expression can restore that transition. (C) JUN overexpression can activate cells viability. By silencing PTX3 expression simultaneously can inhibit cells viability. NS, no significantly statistical; *P < 0.05; **P < 0.01; ***P < 0.001.