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. 2020 Aug 26;11:2053. doi: 10.3389/fmicb.2020.02053

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Copyright © 2020 Fang, Tang, Yang, Alalaiwe, Yang, Tseng and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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In vivo topical application of TCH-1140 against ATCC10231: (A) the skin surface of ATCC10231-infected mice after treatment of 5-FC or TCH-1140 viewed under phenotypic and microscopic images; (B) ATCC10231 CFU in mouse skin after treatment of 5-FC or TCH-1140; (C) TEWL of ATCC10231-infected mice after treatment of 5-FC or TCH-1140; and (D) histological observation of ATCC10231-infected mouse skin biopsy stained by H&E. All data are presented as the mean of six experiments ±SD. ***p < 0.001, **p < 0.01, *p < 0.05.