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. 2020 Aug 26;11:2032. doi: 10.3389/fmicb.2020.02032

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Copyright © 2020 Rodríguez-Daza, Roquim, Dudonné, Pilon, Levy, Marette, Roy and Desjardins.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Bacterial biomarkers in mice fed the polyphenol-rich CP and BP and their fiber-rich CF and BF. Key phylotypes were identified using linear discriminant analysis (LDA) combined with effect size (LEfSe) algorithm. (A) LEfSe analysis showing taxa distinguishing Chow-fed mice (CT) as compared to HFHS (HF); (B) Taxa distinguishing mice fed polyphenol-rich whole cranberry powder (CP); (C) Taxa distinguishing mice fed polyphenol-rich whole blueberry powder (BP); (D) Taxa distinguishing mice fed fiber-rich cranberry fraction (CF); and (E) Taxa distinguishing mice fed fiber-rich blueberry fractions (BF). Threshold for LDA score was 2.0. Positive LDA (green bars) are enriched in HF, while negative LDA (red bars) are enriched in CT, CP, BP, CF, and BF as shown on figure legends (n = 12 mice per group). Statistically significant taxa enrichment was obtained with Kruskal–Wallis test among classes (p-value = 0.05).