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. 2020 Aug 26;10:1404. doi: 10.3389/fonc.2020.01404

Table 3.

Common adverse events of clinical and laboratory abnormalities.

Adverse event Grade 1/2 Grade 3/4 Patients, n (%)
Chemotherapy TKIs treatment Chemotherapy TKIs treatment
Non-hematologic
Hypertension 0 1 0 0 1 (4.5%)
Mucositis 0 1 0 0 1 (4.5%)
Hypothyroidism 1 2 0 1 4 (18.2%)
Fatigue 1 2 0 0 1 (4.5%)
Diarrhea 1 4 0 0 5 (22.7%)
Upper gastrointestinal bleeding 0 0 0 1 1 (4.5%)
Hypophysitis 1 1 0 0 2 (9.1%)
Anorexia 3 3 0 0 6 (27.3%)
Albuminuria 0 1 0 0 1 (4.5%)
Hyperbilirubinemia 0 1 0 0 1 (4.5%)
Hematologic
Hemoglobin 0 0 0 1 1 (4.5%)
Leukocyte 0 0 1 0 1 (4.5%)
Platelets 0 0 1 0 1 (4.5%)