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CD47 up-regulation activated PI3K/Akt/mTOR signaling pathway in HEC-1A and Ishikawa cell lines. (A–C) CD47 overexpression increased expression levels of PI3K, Akt, and mTOR proteins. (D–G) CD47 down-regulation decreased expression levels of PI3K, Akt, and mTOR proteins. *p < 0.05.
