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. 2020 Aug 26;14:875. doi: 10.3389/fnins.2020.00875

FIGURE 1.

FIGURE 1

Overview of TH action in the subventricular zone and on oligodendroglial lineage cells and their contribution to repair in multiple sclerosis. Key genes are in italic next to arrows. Abbreviations: EC, endothelial cell; FAAH, fatty acid amide hydrolase; NPC, neural precursor cell; NSC, neural stem cell; OL, oligodendrocyte; Sob, sobetirome; SobAM2, methyl amide-derivative of sobetirome; SVZ, subventricular zone; SVZ-OPC, SVZ-derived oligodendrocyte precursor cell; pOPC, parenchymal oligodendrocyte precursor cell; TAP, transient amplifying progenitor; TTR, transthyretin.