Figure 1.

Scheme of Subretinal AAV Injection

(A) Scheme of AAV9-based subretinal administration. (B) Representative FP, FFA, and OCT images of the right eye, showing the structure of the retina before AAV injection. (C) Representative FP and OCT images monitor the puncture sites and AAV vacuoles on injection day 1. Punctures are indicated by dotted colored polygons, and the foveae are indicated with dotted circles in yellow. (D) Representative FP, FFA, and OCT images indicate the recovery of the retina after puncture at days 3, 8, and 30. Green arrows in the FP images show the imaging site of the OCT, and green triangles in the OCT images indicate the puncture sites.