Table 1.
Number of crossing and rearing and time spent in the centre of the open field.
| Parameters | Control | Scopo | Doses of C. edulis (mg/kg) | Donepezil | |||
|---|---|---|---|---|---|---|---|
| 62.8 | 157 | 314 | 628 | ||||
| Number of crossing | 80.4 ± 2.8 | 50.8 ± 3.1### | 65.4 ± 2.0∗∗∗ | 69.8 ± 3.4∗∗∗ | 72.6 ± 4.7∗∗∗ | 75.6 ± 2.7∗∗∗ | 78.6 ± 1.8∗∗∗ |
| Number of rearing | 10.6 ± 1.9 | 5.8 ± 0.8### | 6.2 ± 0.8 | 7.2 ± 0.8 | 8 ± 1.5 | 8.6 ± 01.1∗ | 9.4 ± 1.1∗∗ |
| Time spent | 5.4 ± 1.1 | 2.4 ± 0.8### | 2.8 ± 0.8 | 3.2 ± 1.0 | 4.2 ± 1.1∗ | 4.8 ± 0.8∗∗ | 5.2 ± 2.0∗∗∗ |
Each value represents the mean ± SEM (n = 5). The number of crossing and rearing decreases for the Scopolamine group (###p < 0.001 vs. control), and the administration of C. edulis aqueous extract increases this number of crossing and rearing (∗p < 0.05, ∗∗p < 0.01, and ∗∗∗p < 0.001 vs. Scopo). One-way ANOVA followed by the Tukey multiple comparison test. Scopo: Scopolamine.