Fig. 1.

(a) Overview of analytic methods. Patient-derived tumour xenografts (PDX) were generated from human tumour biopsies from TNBC patients. Human imaging was performed on the Siemens mMR PET/MR scanner. PDX were imaged on Agilent 4.7T or MR Solutions 7T MR scanner. Radiomics analysis, including histogram (1st order), grey level co-occurrence matrix (GLCM) or second order and higher order features, was performed on 2D and 3D segmented tumours to assess volume dependency, sensitivity to noise, and sensitivity of resolution. (b). Growth profile of TNBC PDX used in this study based on calliper measurements.