Table II.
Logistic regression analysis for predictors of papillary thyroid carcinoma risk in patients with thyroid nodules.
| Univariate analysis | Multivariate analysisa | |||||
|---|---|---|---|---|---|---|
| Characteristic | OR | 95% CI | P-value | OR | 95% CI | P-value |
| Sex | ||||||
| Female | 1.00 | 1.00 | ||||
| Male | 1.398 | 0.669–2.919 | 0.373 | 1.405 | 0.643–3.071 | 0.394 |
| Age, years | ||||||
| >45 | 1.00 | 1.00 | ||||
| ≤45 | 5.186 | 2.217–12.134 | <0.001 | 5.192 | 2.215–12.171 | <0.001 |
| Smoking habit | ||||||
| Smoker | 1.00 | 1.00 | ||||
| Non-smoker | 0.604 | 0.206–1.767 | 0.357 | 0.848 | 0.248–2.892 | 0.792 |
| BMI, kg/m2 | ||||||
| <4.0 | 1.00 | 1.00 | ||||
| ≥24.0 | 1.765 | 0.901–3.458 | 0.098 | 1.914 | 0.959–3.821 | 0.066 |
| Multifocality | 0.291 | 0.140–0.602 | 0.001 | 0.334 | 0.154–0.724 | 0.005 |
| Bilaterality | 0.774 | 0.388–1.541 | 0.465 | 0.979 | 0.478–2.135 | 1.010 |
| UIC, µg/l | ||||||
| 100-299 | 1.00 | 1.00 | ||||
| <100 | 2.546 | 1.135–5.712 | 0.023 | 2.252 | 0.943–5.375 | 0.067 |
| ≥300 | 3.359 | 1.297–8.701 | 0.013 | 3.987 | 1.355–11.736 | 0.012 |
| UIC/creatinine, µg/µmol | ||||||
| 2.0–9.9 | 1.00 | 1.00 | ||||
| <2.0 | 1.845 | 0.696–4.887 | 0.218 | 2.107 | 0.722–6.148 | 0.173 |
| ≥10.0 | 2.167 | 0.779–6.033 | 0.139 | 2.516 | 0.822–7.698 | 0.106 |
a
Adjusted potential covariates such as sex, age, smoking habits and BMI. OR, odds ratio; CI, confidence interval; BMI, body mass index; UIC, urinary iodine concentration.