FIGURE 2.

Predominant histomorphologic and cytologic features of GNET. A, GNET involvement of the bowel wall and mucosal invasion with tumor cells infiltrating the lamina propria. B, GNET with a predominant solid pattern; note the lack of clear cell morphology. C, GNET with occasional melanoma-like nesting pattern and clear cell features. D, High magnification of typical GNET cytology. Cells are epithelioid and polygonal with eosinophilic cytoplasm. Pleomorphic nuclei showed vesicular chromatin, prominent nucleoli, and occasional intranuclear cytoplasmic inclusions (arrow).