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. 2020 Sep 8;10:14745. doi: 10.1038/s41598-020-71593-8

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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M101 up-regulates the gene expression of pro-resolutive Resolvin-E1 receptor in P. gingivalis-induced inflammation in EC. The expression levels amongst untreated EC, M101-treated EC, Pg-infected EC and M101 treated Pg-infected EC were compared. M101 treatment (1 g/L) for 6 h increased the relative mRNA expression of resolvin-E1 receptor in untreated and Pg-infected EC (MOI = 100). Data are expressed as the mean ± SD. ^†Difference versus untreated EC, p < 0.05, *difference versus Pg-infected EC, p < 0.05.