Table 1:

Summary of the utility of biomarkers in prediction of clinical reactivity and key clinical parameters

Biomarker	Allergy Y/N	Threshold	Severity	Natural Resolution	Response to IT
Food-specific IgE	++	+	+/−	+	+
Component-specific IgE	++	−	−	+	+
Food-specific IgG	−	−	−	−	+
Food-specific IgA	−	−	−	−	+
Epitope-specific IgE	++	ND	ND	ND	++
Basophil Activation Test	+++	++	++	+	++
Food-specific T cell	+	+	ND	+	+
Transcriptomics	+	ND	+	ND	ND
Epigenomics	+	ND	+	ND	ND
Microbiome	+	ND	ND	+	ND
Metabolomics	−/+	ND	ND	ND	ND

ND = not done. − not predictive, + some evidence, +++ strong evidence, −/+ data for and against