TABLE 7.
Multivariate Model | |||||
---|---|---|---|---|---|
Model | (df) F | FDR–corr. P | Adj. R2 | Univariate Predictors | P |
#1 | (4,15) 3.279 | 0.065^ | 0.324 | PC2: β = 0.796, SE = 0.377, t = 2.113 | 0.052^ |
Age: β = 0.052, SE = 0.043, t = 1.194 | 0.251 | ||||
Days Assess–MRI: β = −0.005, SE = 0.005, t = −0.998 | 0.334 | ||||
T2 CHS Ventricles: β = −0.529, SE = 0.283, t = −1.867 | 0.082 | ||||
#2 | (4,15) 6.258 | 0.029* | 0.525 | PC2: β = 0.791, SE = 0.307, t = 2.576 | 0.021* |
Age: β = 0.086, SE = 0.038, t = 2.235 | 0.041* | ||||
Days Assess–MRI: β = −0.006, SE = 0.004, t = −1.425 | 0.175 | ||||
T2 CHS WM: β = −0.728, SE = 0.216, t = −3.364 | 0.004** | ||||
#3 | (4,15) 4.344 | 0.045* | 0.413 | PC2: β = 0.841, SE = 0.340, t = 2.472 | 0.026* |
Age: β = 0.037, SE = 0.036, t = 1.015 | 0.326 | ||||
Days Assess–MRI: β = −0.005, SE = 0.005, t = −1.000 | 0.333 | ||||
T2 Fazekas PVH: β = −1.342, SE = 0.535, t = −2.507 | 0.024* | ||||
#4 | (4,15) 4.246 | 0.045* | 0.406 | PC2: β = 1.053, SE = 0.335, t = 3.139 | 0.007** |
Age: β = 0.054, SE = 0.039, t = 1.381 | 0.188 | ||||
Days Assess–MRI: β = −0.006, SE = 0.004, t = −1.440 | 0.170 | ||||
T2 Fazekas DWMH: β = −1.225, SE = 0.499, t = −2.455 | 0.027* |
Univariate predictors in each numbered model include a visual rating metric plus predictors from the base model.
Significant at P < 0.05.
Significant at P < 0.01.
Significant at P < 0.001.
0.08 < > 0.05.
CHS = Cardiovascular Health Study. Days Assess–MRI = number of days between assessment and MRI dates. df = degree of freedom. DWMH = deep white matter hyperintensities. FDR = false discovery rate. PC = principal component. PVH = periventricular hyperintensities. WM = white matter.