Table 2.
Sex | Protocol | N | Lowest HR (beats/min) | Time to Lowest HR (min.) | Lowest RR (breaths/min) | Time to Lowest RR (min) | |
BALB/c | |||||||
EX | 19 | 254.06 ± 19.03(16) | 37.31 ± 21.47(16) | 115.79 ± 13.05(19) | 21.84 ± 18.29(19) | ||
KX | 18 | 248.91 ± 3.56(11) | 11.36 ± 10.52(11) | 111.67 ± 8.57(18) | 27.11 ± 14.92(18) | ||
F | EX | 10 | 257.63 ± 20.50(8) | 27.88 ± 19.92(8) | 114.00 ± 13.50(10) | 26.80 ± 18.63(10) | |
KX | 8 | 248.17 ± 4.79(6) | 11.83 ± 14.43(6) | 110.00 ± 7.56(8) | 24.38 ± 14.86(8) | ||
M | EX | 9 | 250.50 ± 18.08(8) | 46.75 ± 19.67(8) | 117.78 ± 13.02(9) | 16.33 ± 17.23(9) | |
KX | 10 | 249.80 ± 1.10(5) | 10.80 ± 3.96(5) | 113.00 ± 9.49(10) | 29.30 ± 15.38(10) | ||
C57BL/6 | |||||||
EX | 17 | 278.00 ± 31.02(17) | 35.35 ± 22.09(17) | 102.35 ± 13.93(17) | 21.24 ± 18.85(17) | ||
KX | 17 | 251.00 ± 10.81(16) | 24.13 ± 14.65(16) | 114.12 ± 12.28(17) | 34.82 ± 22.86(17) | ||
F | EX | 9 | 292.11 ± 35.64(9) | 25.56 ± 19.76(9) | 101.11 ± 18.33(9) | 18.78 ± 23.34(9) | |
KX | 9 | 257.13 ± 12.10(8) | 14.88 ± 6.24(8) | 115.56 ± 15.09(9) | 29.11 ± 12.89(9) | ||
M | EX | 8 | 262.13 ± 14.29(8) | 46.38 ± 20.16(8) | 103.75 ± 7.44(8) | 24.00 ± 13.16(8) | |
KX | 8 | 244.88 ± 4.29(8) | 33.38 ± 15.00(8) | 112.50 ± 8.86(8) | 41.25 ± 30.26(8) | ||
CD1 | |||||||
EX | 22 | 274.18 ± 28.78(17) | 13.35 ± 7.57(17) | 93.33 ± 13.90(21) | 11.33 ± 6.35(21) | ||
KX | 20 | 265.75 ± 26.74(20) | 19.65 ± 11.52(20) | 103.00 ± 13.02(20) | 17.40 ± 8.25(20) | ||
F | EX | 12 | 269.10 ± 23.63(10) | 14.20 ± 8.85(10) | 90.00 ± 14.14(12) | 12.08 ± 7.15(12) | |
KX | 11 | 269.18 ± 33.86(11) | 16.55 ± 3.75(11) | 100.00 ± 10.95(11) | 17.64 ± 6.86(11) | ||
M | EX | 10 | 281.43 ± 35.59(7) | 12.14 ± 5.67(7) | 97.78 ± 13.02(9) | 10.33 ± 5.34(9) | |
KX | 9 | 261.56 ± 15.13(9) | 23.44 ± 16.37(9) | 106.67 ± 15.00(9) | 17.11 ± 10.13(9) | ||
NU | |||||||
EX | 16 | 277.00 ± 26.65(16) | 31.88 ± 13.75(16) | 95.00 ± 7.30(16) | 8.88 ± 5.80(16) | ||
KX | 18 | 254.22 ± 9.83(18) | 22.56 ± 14.89(18) | 113.33 ± 10.85(18) | 21.50 ± 11.35(18) | ||
F | EX | 8 | 288.00 ± 28.40(8) | 34.50 ± 16.41(8) | 97.50 ± 8.86(8) | 9.38 ± 4.21(8) | |
KX | 9 | 257.22 ± 12.79(9) | 20.78 ± 9.95(9) | 114.44 ± 14.24(9) | 17.89 ± 7.75(9) | ||
M | EX | 8 | 266.00 ± 20.96(8) | 29.25 ± 10.95(8) | 92.50 ± 4.63(8) | 8.38 ± 7.33(8) | |
KX | 9 | 251.22 ± 4.60(9) | 24.33 ± 19.10(9) | 112.22 ± 6.67(9) | 25.11 ± 13.58(9) | ||
Total | |||||||
F | EX | 39 | 276.71 ± 29.91(35) | 24.89 ± 17.53(35) | 100.26 ± 16.46(39) | 16.85 ± 16.15(39) | |
KX | 37 | 259.47 ± 21.88(34) | 16.44 ± 8.81(34) | 109.46 ± 13.53(37) | 21.95 ± 11.41(37) | ||
M | EX | 35 | 264.48 ± 24.52(31) | 34.32 ± 20.52(31) | 103.24 ± 13.87(34) | 14.68 ± 12.79(34) | |
KX | 36 | 252.35 ± 10.63(31) | 24.23 ± 16.61(31) | 111.11 ± 10.36(36) | 27.86 ± 19.56(36) | ||
All | |||||||
EX | 74 | 270.97 ± 27.99(66) | 29.32 ± 19.43(66) | 101.64 ± 15.28(73) | 15.84 ± 14.62(73) | ||
KX | 73 | 256.08 ± 17.68(65) | 20.15 ± 13.59(65) | 110.27 ± 12.02(73) | 24.86 ± 16.13(73) |
Mean ± SD(n) for each outcome is presented, n represents captured mice.
EX: Etomidate/Xylazine; F: female; KX:Ketamine/Xylazine; M: Male