Table 3.
Hematologic values (mean ± standard deviation) for the 3 groups at the different time points
| Control |
Bup |
BupSR |
BupHC |
||||||||
| 0 h (n = 8) | 96 h (n = 9) | 0 h (n = 5) | 48 h (n = 7) | 96 h (n = 7) | 0 h (n = 8) | 48 h (n = 8) | 96 h (n = 8) | 0 h (n = 7) | 48 h (n = 7) | 96 h (n = 6) | |
| RBC (×106/µL) | 6.4 ± 0.5 | 6.0 ± 0.8 | 6.0 ± 0.3 | 4.7 ± 0.2 | 4.8 ± 0.6 | 6.3 ± 0.5 | 5.1 ± 0.5 | 4.8 ± 0.4 | 6.0 ± 0.3 | 5.1 ± 0.2 | 4.5 ± 0.4 |
| Hgb (g/dL) | 13.5 ± 1.2 | 12.6 ± 1.7 | 13.0 ± 0.8 | 10.2 ± 0.5 | 10.4 ± 1.2 | 13.1 ± 0.9 | 10.6 ± 0.8 | 10.0 ± 0.7 | 12.7 ± 0.7 | 10.6 ± 0.6 | 9.6 ± 0.7 |
| Hct (%) | 41.0 ± 3.8 | 39.6 ± 4.5 | 39.6 ± 2.2 | 33.7 ± 2.8 | 33.5 ± 2.8 | 40.1 ± 2.8 | 33.7 ± 3.3 | 33.4 ± 2.9 | 38.7 ± 2.3 | 33.6 ± 2.3 | 31.5 ± 2.5 |
| MCV (fL) | 63.9 ± 1.5 | 67.1 ± 4.6 | 66.4 ± 3.6 | 71.6 ± 6.5 | 69.7 ± 5.4 | 63.4 ± 2.3 | 66.9 ± 4.3 | 68.9 ±4.0 | 64.4 ± 2.9 | 66.3 ± 3.3 | 69.5 ± 4.4 |
| MCH (pg) | 21.1 ± 0.4 | 21.3 ± 0.8 | 21.8 ± 1.0 | 21.6 ± 0.9 | 21.5 ± 1.0 | 20.7 ± 0.8 | 21.0 ± 0.6 | 20.7 ± 0.7 | 21.1 ± 0.8 | 20.9 ± 0.7 | 21.1 ± 0.8 |
| MCHC (g/dL) | 33.1 ± 0.5 | 31.8 ± 1.3 | 32.9 ± 0.7 | 30.4 ± 3.2 | 30.9 ± 1.4 | 32.7 ± 0.4 | 31.5 ± 1.5 | 30.4 ± 2.4 | 32.8 ± 0.3 | 31.6 ± 1.3 | 30.4 ± 1.0 |
| WBC (×103/uL) | 8.6 ± 2.2 | 9.3 ± 1.1 | 8.3 ± 0.8 | 9.6 ± 1.7 | 8.9 ± 1.5 | 8.2 ± 1.4 | 9.0 ± 1.5 | 8.9 ± 1.7 | 7.1 ± 1.0 | 7.2 ± 1.3 | 7.8 ± 1.6 |
| Neutrophils (%) | 22.0 ± 8.9 | 32.2 ± 13.0 | 37.4 ± 9.4 | 35.7 ± 5.5 | 32.4 ± 10.5 | 27.1 ± 10.3 | 42.7 ± 8.9 | 32.1 ± 12.4 | 24.0 ± 8.3 | 36.6 ± 9.1 | 31.8 ± 5.1 |
| Lymphocytes (%) | 69.1 ± 12.3 | 61.3 ± 11.5 | 53.1 ± 5.9 | 55.2 ± 6.5 | 58.1 ± 12.6 | 65.3 ± 9.8 | 47.6 ± 9.8 | 60.2 ± 15.4 | 65.9 ± 10.7 | 52.2 ± 9.8 | 55.4 ± 6.5 |
| Monocytes (%) | 4.8 ± 2.8 | 3.2 ± 2.0 | 5.3 ± 2.8 | 6.0 ± 1.9 | 6.7 ± 1.5 | 4.2 ± 2.9 | 6.1 ± 1.2 | 5.0 ± 4.3 | 6.1 ± 2.7 | 7.6 ± 1.4 | 8.7 ± 3.3 |
| Eosinophils (%) | 1.7 ± 1.2 | 1.3 ± 1.3 | 1.2 ± 1.2 | 0.9 ± 0.5 | 1.3 ± 0.6 | 1.0 ± 0.7 | 1.2 ± 0.6 | 1.5 ± 1.6 | 1.1 ± 0.9 | 0.8 ± 0.2 | 1.5 ± 0.5 |
| Basophils (%) | 2.5 ± 0.9 | 2.0 ± 1.2 | 3.1 ± 2.4 | 2.2 ± 1.8 | 1.6 ± 1.4 | 2.5 ± 1.6 | 2.5 ± 1.0 | 1.2 ± 1.2 | 2.9 ± 1.6 | 2.8 ± 1.5 | 2.7 ± 1.1 |