Table 3.
Characteristic | Total | ELR group | LLR group | P-value |
---|---|---|---|---|
(n = 182)% | (n = 87)% | (n = 95)% | ||
Age (years) | 0.088 | |||
≤46 years | 101 (55.5) | 54 (62.1) | 47 (49.5) | |
>46 years | 81 (44.5) | 33 (37.9) | 48 (50.5) | |
Gender | 0.162 | |||
Male | 138 (75.8) | 70 (80.5) | 68 (71.6) | |
Female | 44 (24.2) | 17 (19.5) | 27 (28.4) | |
Smoking status | 0.870 | |||
Non-smoker | 112 (61.5) | 53 (60.9) | 59 (62.1) | |
Smoker | 70 (38.5) | 34 (39.1) | 36 (37.9) | |
Alcohol abuse | 0.569 | |||
Non-drinker | 154 (84.6) | 75 (86.2) | 79 (83.2) | |
Drinker | 28 (15.4) | 12 (13.8) | 16 (16.8) | |
Tumor family history | 0.603 | |||
No | 137 (75.3) | 67 (77.0) | 70 (73.7) | |
Yes | 45 (24.7) | 20 (23.0) | 25 (26.3) | |
Cranial nerve symptom | 0.427 | |||
N0 | 172 (94.5) | 81 (93.1) | 91 (95.8) | |
Yes | 10 (5.5) | 6 (6.9) | 4 (4.2) | |
Baseline value of EBV-DNA | 0.728 | |||
≤2,000 | 63 (34.6) | 29 (33.3) | 34 (35.8) | |
>2,000 | 119 (65.4) | 58 (66.7) | 61 (64.2) | |
Histological type | 0.246 | |||
WHO I/II | 10 (5.5) | 3 (3.4) | 7 (7.4) | |
WHO III | 172 (94.5) | 84 (96.6) | 88 (92.6) | |
T stage | 0.552 | |||
1/2 | 39 (21.4) | 17 (19.5) | 22 (23.2) | |
3/4 | 143 (78.6) | 70 (80.5) | 73 (76.8) | |
N stage | 0.316 | |||
0/1 | 97 (53.3) | 43 (49.4) | 54 (56.8) | |
2/3 | 85 (46.7) | 44 (50.6) | 41 (43.2) | |
TNM stage | 0.826 | |||
I/II | 22 (12.1) | 11 (12.6) | 11 (11.6) | |
III/IV | 160 (87.9) | 76 (87.4) | 84 (88.4) | |
Induction chemotherapy | 0.399 | |||
No | 77 (42.3) | 34 (39.1) | 43 (45.3) | |
Yes | 105 (57.7) | 53 (60.9) | 52 (54.7) | |
Concurrent chemotherapy | 0.203 | |||
No | 29 (15.9) | 17 (19.5) | 12 (12.6) | |
Yes | 153 (84.1) | 70 (80.5) | 83 (87.4) | |
Adjuvant chemotherapy | 0.065 | |||
No | 173 (95.1) | 80 (92.0) | 93 (97.9) | |
Yes | 9 (4.9) | 7 (8.0) | 2 (2.1) | |
Post-recurrence treatment options | 0.415 | |||
BST | 9 (4.9) | 5 (5.7) | 4 (4.2) | |
Salvage surgery | 43 (23.6) | 22 (25.3) | 21 (22.1) | |
Re-irradiation | 70 (38.5) | 28 (32.2) | 42 (44.2) | |
Chemotherapy | 60 (33.0) | 32 (36.8) | 28 (29.5) |