Skip to main content
. 2020 Aug 25;10:1469. doi: 10.3389/fonc.2020.01469

Table 3.

Comparison of clinical characteristics of ELR and LLR patients in the locoregional recurrence group.

Characteristic Total ELR group LLR group P-value
(n = 182)% (n = 87)% (n = 95)%
Age (years) 0.088
≤46 years 101 (55.5) 54 (62.1) 47 (49.5)
>46 years 81 (44.5) 33 (37.9) 48 (50.5)
Gender 0.162
Male 138 (75.8) 70 (80.5) 68 (71.6)
Female 44 (24.2) 17 (19.5) 27 (28.4)
Smoking status 0.870
Non-smoker 112 (61.5) 53 (60.9) 59 (62.1)
Smoker 70 (38.5) 34 (39.1) 36 (37.9)
Alcohol abuse 0.569
Non-drinker 154 (84.6) 75 (86.2) 79 (83.2)
Drinker 28 (15.4) 12 (13.8) 16 (16.8)
Tumor family history 0.603
No 137 (75.3) 67 (77.0) 70 (73.7)
Yes 45 (24.7) 20 (23.0) 25 (26.3)
Cranial nerve symptom 0.427
N0 172 (94.5) 81 (93.1) 91 (95.8)
Yes 10 (5.5) 6 (6.9) 4 (4.2)
Baseline value of EBV-DNA 0.728
≤2,000 63 (34.6) 29 (33.3) 34 (35.8)
>2,000 119 (65.4) 58 (66.7) 61 (64.2)
Histological type 0.246
WHO I/II 10 (5.5) 3 (3.4) 7 (7.4)
WHO III 172 (94.5) 84 (96.6) 88 (92.6)
T stage 0.552
1/2 39 (21.4) 17 (19.5) 22 (23.2)
3/4 143 (78.6) 70 (80.5) 73 (76.8)
N stage 0.316
0/1 97 (53.3) 43 (49.4) 54 (56.8)
2/3 85 (46.7) 44 (50.6) 41 (43.2)
TNM stage 0.826
I/II 22 (12.1) 11 (12.6) 11 (11.6)
III/IV 160 (87.9) 76 (87.4) 84 (88.4)
Induction chemotherapy 0.399
No 77 (42.3) 34 (39.1) 43 (45.3)
Yes 105 (57.7) 53 (60.9) 52 (54.7)
Concurrent chemotherapy 0.203
No 29 (15.9) 17 (19.5) 12 (12.6)
Yes 153 (84.1) 70 (80.5) 83 (87.4)
Adjuvant chemotherapy 0.065
No 173 (95.1) 80 (92.0) 93 (97.9)
Yes 9 (4.9) 7 (8.0) 2 (2.1)
Post-recurrence treatment options 0.415
BST 9 (4.9) 5 (5.7) 4 (4.2)
Salvage surgery 43 (23.6) 22 (25.3) 21 (22.1)
Re-irradiation 70 (38.5) 28 (32.2) 42 (44.2)
Chemotherapy 60 (33.0) 32 (36.8) 28 (29.5)