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. 2020 Aug 25;10:1469. doi: 10.3389/fonc.2020.01469

Table 5.

Univariate and multivariate analysis of prognostic factors of ENR and LNR in the purely regional recurrence group.

Characteristic ETR group LTR group
Univariate P-value HR (95% CI) Multivariate P-value Univariate P-value HR (95% CI) Multivariate P-value
Age (years) 0.437 NS 0.997 NS
≤46 years
>46 years / /
Gender 0.749 NS 0.885 NS
Male
Female / /
Smoking status 0.264 NS 0.705 NS
Non-smoker
Smoker / /
Alcohol abuse 0.032 0.001 0.970 NS
Non-drinker Reference
Drinker 3.070 (1.551–6.076) /
Tumor family history 0.599 NS 0.796 NS
No
Yes / /
Cranial nerve symptom 0.035 NS 0.315 NS
No
Yes / /
Baseline value of EBV-DNA 0.090 NS 0.323 / NS
≤2,000
>2,000 / /
Histological type 0.979 NS 0.234 NS
WHO I/II
WHO III / /
T stage 0.353 NS 0.580 NS
1/2
3/4 / /
N stage 0.048 NS 0.192 NS
0/1
2/3 / /
TNM stage 0.037 0.016 0.494 NS
I/II Reference
III/IV 2.394 (1.178–4.864) /
RT+/Chemo 0.823 NS 0.740 NS
RT alone
RT+Chemo / /