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. 2020 Aug 25;10:1469. doi: 10.3389/fonc.2020.01469

Table 6.

Univariate and multivariate analysis of prognostic factors of ELR and LLR in the locoregional recurrence group.

Characteristic ETR group LTR group
Univariate P-value HR (95% CI) Multivariate P-value Univariate P-value HR (95% CI) Multivariate P-value
Age(years) 0.069 NS 0.063 NS
≤46 years
>46 years / /
Gender 0.837 NS 0.101 NS
Male
Female / /
Smoking status 0.245 NS 0.483 NS
Non-smoker
Smoker / /
Alcohol abuse 0.194 NS 0.817 NS
Non-drinker
Drinker / /
Tumor family history 0.106 NS 0.095 NS
No
Yes / /
Cranial nerve symptom 0.139 NS 0.771 NS
No
Yes / /
Baseline value of EBV-DNA 0.110 NS 0.600 NS
≤2,000
>2,000 / /
Histological type 0.646 NS 0.392 NS
WHO I/II
WHO III / /
T stage 0.557 NS 0.020 0.019
1/2 Reference
3/4 / 3.675 (1.241–10.882)
N stage 0.026 0.004 0.966 NS
0/1 Reference
2/3 2.391 (1.328–4.271) /
TNM stage 0.363 0.002 0.047 NS
I/II Reference
III/IV 1.874 (1.248–2.812) /
RT+/Chemo 0.765 NS 0.403 NS
RT alone
RT+Chemo / /