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. 2020 Aug 25;11:1076. doi: 10.3389/fphys.2020.01076

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Copyright © 2020 de Araújo, Costa-Pessoa, de Ponte and Oliveira-Souza.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of NaOx treatment on cortical changes, including tubular injury, as demonstrated by HE staining (A). Urine samples from control and treated rats were resolved on 10% SDS page gels followed by gel staining with a protein-sensitive SilverQuest Silver Staining Kit. Statistical analysis of albumin excretion in both the control and treated groups was performed (B,C). The mRNA expression levels of Kim-1 (D) and Ki67 (E). The values are mean ± SE (n = 6–8). Bar = 100 μm. CTL, control; NaOx, sodium oxalate; G glomerulus; PT, proximal tubule.