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. 2020 Aug 25;11:1076. doi: 10.3389/fphys.2020.01076

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Copyright © 2020 de Araújo, Costa-Pessoa, de Ponte and Oliveira-Souza.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Representative photomicrographs of the renal cortex illustrating tubulointerstitial CD68-positive cells (indicated by arrows) by immunohistochemistry. Images were captured using a morphometric program (NIS-Elements, Nikon) with a 20× objective and magnified images shown at the top were captured with a 40× objective. The values represent the mean ± SE (A,B). Bar = 100 μm. In addition, MCP-1 (C), IL-β1 (D) NFkappaB (E) and α-SMA (F) mRNA expression levels are shown as the mean ± SE (n = 5–8/group). CTL, control; NaOx, sodium oxalate.