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Characterization of the wild type and mutant CTPS enzymes.
| Enzyme | Initial | Km | Vmax | IQC IC50 |
| rate | (mM UTP) | (pmol CTP min–1) | (μg mL–1) | |
| WT | 0.14 | 2.3 ± 0.19 | 0.23 ± 0.01 | 94 ± 5 |
| Mutant 1 | 0.01 | 1.2 ± 0.13 | 0.08 ± 0.00 | 450 ± 20 |
| Mutant 5 | 0.14 | 1.2 ± 0.07 | 0.19 ± 0.00 | 100 ± 7 |
| Mutant 11 | 0.26 | 1.2 ± 0.12 | 0.25 ± 0.01 | 240 ± 10 |
