Table 1. Performance of siRNA silencing efficacy of our model, pssRNAit, and five other tools on training dataset TR2431 and testing dataset TE419.
Values represent the Pearson correlation coefficient between observed and predicted siRNA efficacy. Dataset TR2431 was used to train the models, whereas dataset TE419 was used as an independent test set. The asterisk indicates the Pearson correlation coefficient of desiRm obtained for dataset TR2182.
Algorithms | TR2431 | TE419 |
---|---|---|
i-Score | 0.635 | 0.557 |
s-Biopredsi | 0.665 | 0.546 |
ThermoComposition21 | 0.635 | 0.577 |
DSIR | 0.687 | 0.554 |
desiRm* | 0.670* | 0.558 |
pssRNAit | 0.709 | 0.568 |