Figure 3.

Effect of NEO2734 on cell cycle and MYC protein level in DLBCL cell lines. (A) Representative cell cycle profiles of 2 replicates with the respective quantification; 2 GCB-DLBCL (TOLEDO, DOHH2) and 2 ABC-DLBCL (SU-DHL-2, TMD8) cell lines were treated with DMSO or birabresib (300 nM) or NEO2734 (300 nM) or SGC-CBP30 (10 μM) for 72 hours. (B) Representative immunoblot of 2 replicates. Two GCB-DLBCLs and 2 ABC-DLBCLs were exposed to NEO2734 (250 nM) for 24 hours. (C) Immunoblot quantification.