. Author manuscript; available in PMC: 2020 Sep 9.

Published in final edited form as: Am J Phys Anthropol. 2018 Sep 6;167(3):557–568. doi: 10.1002/ajpa.23684

Table 2.

Distal femoral trabecular bone microarchitecture and midshaft femoral cortical bone cross-sectional geometry in male C57BL/6J mice housed at 20, 22, or 26°C from 3 wks to 6 or 12 wks of age (N=8/group)

	6 wks of age						12 wks of age
	20°C (cool)		22°C (control)		26°C (warm)		20°C (cool)		22°C (control)		26°C (warm)
	Mean	SD	Mean	SD	Mean	SD	Mean	SD	Mean	SD	Mean	SD	p_temperature
Distal femur trabecular bone
BV/TV (%)	19.7	4.6	22.5	3.3	22.0	2.9	15.8^*	5.0	15.5^*	1.4	20.4	2.8	0.031
Tb.N (/mm)	5.57	0.62	5.68	0.24	5.83	0.34	4.92^*	0.30	5.03	0.24	5.35	0.34	0.035
Tb.Th (mm)	0.058	0.004	0.063	0.007	0.061	0.005	0.057	0.008	0.056	0.002	0.062	0.005	NS
Tb.Sp (mm)	0.179	0.022	0.174	0.010	0.169	0.010	0.198^*	0.015	0.195	0.011	0.180	0.011	0.018
Conn.D (/mm)	0.327	0.021	0.343	0.019	0.335	0.014	0.387^*	0.015	0.391^*	0.020	0.409	0.015	0.019
Midshaft femur cortical bone
BA/TA (%)	32.7	2.1	34.3	1.9	33.5	1.4	38.7^*	1.5	39.1	2.0	40.9	1.5	0.037
BA (mm²)	0.59	0.04	0.63	0.06	0.62	0.04	0.74	0.07	0.73	0.03	0.78	0.03	NS
TA (mm²)	1.80	0.05	1.84	0.10	1.84	0.10	1.92	0.17	1.88	0.10	1.91	0.07	NS
Ct.Th (mm)	0.140	0.009	0.148	0.013	0.145	0.007	0.174^#	0.009	0.173^*	0.006	0.183	0.008	0.022
Imax (mm⁴)	0.177	0.016	0.197	0.032	0.191	0.026	0.238	0.044	0.236	0.030	0.260	0.017	NS
Imin (mm⁴)	0.093	0.005	0.098	0.014	0.097	0.009	0.118	0.023	0.110	0.009	0.115	0.011	NS
J (mm⁴)	0.269	0.021	0.295	0.044	0.289	0.034	0.356	0.066	0.346	0.036	0.374	0.026	NS

Significant difference vs. warm (p<0.05, GLM and Tukey test);

p=0.053