Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jul 22;219(9):e202003026. doi: 10.1083/jcb.202003026

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 Wang et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 1. — Major neurogenic lineages in the zebrafish retina. (A) Schematic of zebrafish retina structure. OPL, outer plexiform layer. IPL, inner plexiform layer. (B) Schematic of the mMAZe construct. (C) The working flow of lineage analysis of 48-hpf RPCs using mMAZe. (D) Schematic of the atoh7:Switch plasmid (pAtoh7:Switch). (E) The working flow of lineage analysis of atoh7⁺ PRCs using atoh7:Switch. (F) Representatives of major neurogenic lineages traced by mMAZe. (G) Representatives of major neurogenic lineages traced by atoh7:Switch. (H–L) The top four neurogenic lineages, which were analyzed using mMAZe and produce RGCs (H), ACs (I), BCs (J), PRs (K), or HCs (L) are listed. Major neurogenic lineages of each neuron type (frequency >15%) are highlighted in blue. (M–O) The top four lineages, which were analyzed using atoh7:Switch and produce RGCs (M), ACs (N), or BCs (O) are listed. Major neurogenic lineages of each neuron type (frequency >15%) are highlighted in red. (P) Summary graph of six major neurogenic lineages. Scale bars, 10 µm.